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  1. Darieva Z, Zarrineh P, Phillips N, Mallen J, Garcia Mora A, Donaldson I, Bridoux L, Douglas M, Dias Henriques SF, Schulte D, Birket MJ, Bobola N (2024). The evolutionary ancient MEIS transcription factors actuate lineage-specific transcription to establish cardiac fate. BioRxiv.

  2. Lynch AT, Phillips N, Douglas M, Dorgnach M, Lin I, Adamson AD, Darieva Z, Whittle J, Hanley NA, Bobola N, Birket MJ (2024). The level of HAND1 controls the specification of multipotent cardiac and extraembryonic progenitors. BioRxiv.

  3. Lynch AT, Douglas M, Kimber SJ, Birket MJ (2024). The generation and validation of a dual cardiac HAND1-Tomato NKX2-5-GFP human embryonic stem cell line UMANe002-A-3. Stem Cell Res. Jun;77:103342.

  4. Douglas M, O'Loughlin C, Lynch AT, Prialgauskaite R, Adamson AD, Dibb KM, Kimber SJ, Birket MJ (2024). The generation and validation of two NKX2-5 fluorescent reporter human embryonic stem cell lines: UMANe002-A-1 and UMANe002-A-2. Stem Cell Res. Feb;74:1032262.

  5. Gerrard DT, Berry AA, Jennings RE, Birket MJ, Withey SJ, Short P, Jiménez-Gancedo S, Firbas PN, Donaldson I, Sharrocks AD, Piper Hanley K, Hurles ME, Gomez-Skarmeta JL, Bobola N, Hanley NA (2020). The epigenomic landscape regulating organogenesis in human embryos linked to developmental disorders. Nature Communications. Aug 6;11(1):3920.

  6. Schwach V, Fernandes MG, Maas S, Gerhardt S, Tsonaka R, van der Weerd L, Passier RP, Mummery CL, Birket MJ*, Salvatori DCF* (2019). Expandable human cardiovascular progenitors from stem cells for regenerating mouse heart after myocardial infarction. Cardiovascular Res. Jul 9. pii: cvz181. doi: 10.1093/cvr/cvz181. *Authors contributed equally to the work.

  7. Birket MJ, Raibaud S, Lettieri M, Adamson AD, Letang V, Cervello P, Redon N, Bock M, Ret G, Viale S, Wang B, Biton B, Guillemot JC, Mikol V, Leonard JP, Hanley NA, Orsini C, Itier JM (2019). A human pluripotent stem cell model of Fabry disease implicates LIMP-2 accumulation in cardiomyocyte pathology. Stem Cell Rep. Aug 13;13(2):380-393.

    8. Additional scientific and media coverage (click images below to open links in a new window):













  8. Birket MJ, Ribeiro M, Kosmidis G, Ward D, Leitoguinho AR, van de Pol V, Dambrot C, Devalla HD, Davis RP, Mastroberardino P, Passier R, Mummery CL (2015). Contractile defect caused by mutation in MYBPC3 revealed under conditions optimized for human PSC-cardiomyocyte function. Cell Reports. Oct 27; 13(4): 733-45.

  9. Birket MJ, Ribeiro MC, Verkerk AO, Ward D, Leitoguinho AR, Hartogh SC den, Orlova VV, Devalla HD, Schwach V, Bellin M, Passier R, Mummery CL (2015). Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells. Nat. Biotechnol. Sep; 33(9):970-9.

    10. Additional scientific and media coverage (click images below to open links in a new window):













  10. Birket MJ and Mummery CL (2015). Pluripotent stem cell derived cardiovascular progenitors - A developmental perspective. Dev. Biol. 400, 169–179.

  11. Dambrot C, Braam SR, Tertoolen LGJ, Birket M, Atsma DE, Mummery CL (2014). Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes. J. Cell. Mol. Med. 18, 1509–1518.

  12. Birket MJ, Casini S, Kosmidis G, Elliott DA, Gerencser AA, Baartscheer A, Schumacher C, Mastroberardino PG, Elefanty AG, Stanley EG, Mummery CL (2013). PGC-1-α and Reactive Oxygen Species Regulate Human Embryonic Stem Cell-Derived Cardiomyocyte Function. Stem Cell Rep. 1, 560–574.

  13. Gerencser AA, Chinopoulos C, Birket MJ, Jastroch M, Vitelli C, Nicholls DG, Brand MD (2012). Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria. J. Physiol. 590, 2845–2871.

  14. Birket MJ, Orr AL, Gerencser AA, Madden DT, Vitelli C, Swistowski A, Brand MD, Zeng X (2011). A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. J. Cell Sci. 124, 348–358.

  15. Birket MJ, Passos JF, von Zglinicki T, Birch-Machin MA (2009). The relationship between the aging- and photo-dependent T414G mitochondrial DNA mutation with cellular senescence and reactive oxygen species production in cultured skin fibroblasts. J. Invest. Dermatol. 129, 1361–1366.

  16. Ahmed S, Passos JF, Birket MJ, Beckmann T, Brings S, Peters H, Birch-Machin MA, von Zglinicki T, Saretzki G (2008). Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress. J. Cell Sci. 121, 1046–1053.

  17. Birket MJ and Birch-Machin MA (2007). Ultraviolet radiation exposure accelerates the accumulation of the aging-dependent T414G mitochondrial DNA mutation in human skin. Aging Cell 6, 557–564.

  18. Passos JF, Saretzki G, Ahmed S, Nelson G, Richter T, Peters H, Wappler I, Birket MJ, Harold G, Schaeuble K, Birch-Machin MA, Kirkwood TB, von Zglinicki T (2007). Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. PLoS Biol. 5, e110.